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Bone biopsy
Bone biopsy


Definition:

A bone lesion biopsy is the removal of a piece of bone or bone marrow for examination.



Alternative Names:

Bone biopsy; Biopsy - bone



How the test is performed:

The health care provider applies a numbing medicine (local anesthetic) to the area, and makes a small (about 1/8 inch) cut in the skin. A special drill needle is usually used. The biopsy needle is pushed and twisted into the bone.

Once the sample is obtained, the needle is twisted out and the sample is sent for examination. Pressure is applied to the site. Once bleeding stops, the site is cleaned and covered with a bandage.

Bone biopsy may also be done under general anesthesia to remove a larger sample. This may allow for immediate surgery to remove the bone if the exam shows that it is cancerous.



How to prepare for the test:

You may be told not to drink or eat anything for several hours before the biopsy.



How the test will feel:

With a needle biopsy, you may feel moderate discomfort and pressure, even though a local anesthetic is used. You must remain still during the procedure.

After the biopsy, the area may be sore or tender for several days.



Why the test is performed:

The most common reasons for bone lesion biopsy are to tell the difference between cancerous and non-cancerous bone tumors and to identify other bone problem. It may be performed on people with bone pain and tenderness, particularly if x-ray , CT scan, or other testing reveals a problem.



Normal Values:

Normal bone appears as two types: compact and cancellous.

  • Compact bone is dense and contains layers of mineral deposits called lamellae.
  • Cancellous bone looks porous, with widely spaced mineral deposits, and red and yellow marrow in the center of the bone.


What abnormal results mean:

Benign bone tumors include:

Cancerous tumors include:

Abnormal results may also be due to:



What the risks are:
  • Bone fracture
  • Bone infection (osteomyelitis)
  • Damage to surrounding tissue
  • Discomfort
  • Excessive bleeding
  • Infection near the biopsy area

Note: Some people with bone disorders also have blood clotting disorders, which can increase the risk for bleeding.



Special considerations:

Signs of bone infection (one of the most serious risks) include fever, headache, pain with movement, redness and swelling of the tissues around the biopsy site, and drainage of pus from the biopsy site. If these occur, seek immediate medical attention.




Review Date: 7/29/2008
Reviewed By: Thomas N. Joseph, MD, Private Practice specializing in Orthopaedics, subspecialty Foot and Ankle, Camden Bone & Joint, Camden, SC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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