Definition: A cold knife cone biopsy is a procedure to get a sample of abnormal tissue from the cervix for further examination. See also:
Alternative Names: Cone biopsy; Biopsy - cone; Cervical conization
How the test is performed: This is a surgical procedure. It is done in the hospital while you are either sedated through an IV or general anesthesia . The purpose of this procedure is to diagnose and treat precancerous changes in the cervix. A small cone-shaped sample of tissue is removed from the cervix and examined under a microscope for any signs of cancer. This biopsy may also be the treatment if the doctor removes all of the diseased tissue.
How to prepare for the test: As with any procedure that is done under anesthesia, you will probably need to fast for 6 - 8 hours. You must sign an informed consent form. The procedure is done on the same day (outpatient) and a hospital stay is usually not needed.
How the test will feel: After the procedure, you may have some cramping or discomfort for a week or so. For about 4 - 6 weeks avoid: - Douching
- Sexual intercourse
- Using tampons
For 2 - 3 weeks after the procedure, you may have discharge that is: - Bloody
- Heavy
- Yellow-colored
Why the test is performed: This test is only done if the health care provider knows or suspects that you have abnormal cells in the cervix. It may be done if a biopsy of the cervix shows that you may have precancerous cells in the area or cervical cancer . A cold knife biopsy may also be done if a cervical biopsy cannot find the cause of an abnormal Pap smear .
Normal Values: There are no precancerous or cancerous cells in the cervix.
What abnormal results mean: Most often, abnormal results mean that there is an area of precancerous or cancerous cells.
What the risks are: - Bleeding
- Incompetent cervix (which may lead to premature delivery)
- Infection
- Scarring of the cervix (which may cause painful menstrual periods, make it more difficult for doctors to read an abnormal Pap smear, and make it harder to become pregnant)
References: Katz VL, Lentz GM, Lobo RA, Gershenson DM. Comprehensive Gynecology. Philadelphia, Pa: Mosby; 2007.
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