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Blood clots
Blood clots


Definition:

Hemophilia refers to a group of bleeding disorders in which it takes a long time for the blood to clot.

Related topics:



Causes, incidence, and risk factors:

Blood clotting factors are substances in the blood that help form a clot. When one or more of these clotting factors are missing, there is a higher chance of bleeding.

In most cases, the disorder is passed down through families (inherited). It most often affects males.



Symptoms:

The main symptom of hemophilia is bleeding. Mild cases may go unnoticed until later in life, when they occur during surgery or after trauma.

In more severe cases, serious bleeding may occur without any cause. Internal bleeding may occur anywhere. Bleeding into joints is common.



Signs and tests:

Most often, hemophilia is diagnosed after a person has an abnormal bleeding episode or when there is a known family history of the condition.



Treatment: Standard treatment involves replacing the missing clotting factor.

Support Groups:

See: Hemophilia - Resources



Expectations (prognosis):

Most people with hemophilia are able to lead relatively normal lives. However, some patients have significant bleeding events, most commonly chronic bleeding into the joint spaces.

A small percentage of people with hemophilia may die from severe bleeding.



Complications:



Calling your health care provider:



Prevention:



References:

Kumar V, Abbas AK, Fausto N. Robbins and Cotran Pathologic Basis of Disease. 7th ed. St. Louis, Mo: WB Saunders; 2005:655-656.

Kessler C. Hemorrhagic disorders: Coagulation factor deficiencies. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 180.




Review Date: 3/2/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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